
Publications
22
A perfluoro-functionalised fluorescent maleimide probe for imaging of per- and polyfluoroalkyl substances
J. E. Barker, S. D. P. Fielden, R. H. Kempton, C. T. J. Ferguson, R. K. O’Reilly, G. B. Douglas*
Environ. Chem. Lett. 2026, 24, 407–414.

21
They're better, connected: linking up polymer nanoparticles
S. D. P. Fielden*
Trend. Chem. 2026, 8, 15–17

20
Kinetically controlled hetero-fusion is a systems-level behaviour of polymer nanoparticle populations
S. D. P. Fielden,* S. M. Collins, M. J. Derry, C. Ducati, S. M. Fairclough, A. J. Miller, R. K. O’Reilly, P. D. Topham
Nat. Commun. 2025, 16, 11701

19
Crown Ether-Peptide Rotaxanes
P.-L. Wang, P. Chen, R. Yang, D. J. Tetlow, Z.-H. Zhang, J. Han, S. D. P. Fielden, P. Howlader, L. Zhang, D. A. Leigh*
Angew. Chem. Int. Ed. 2025, 64, e202513115

18
Ostwald Ripening as a Tool for Controlling Dynamic Nanomaterials (invited editorial as part of Special Collection: 2025 Emerging Investigators)
S. D. P. Fielden*
Aggregate 2025, 6, e70116.

17
Holding your nerve in academia whilst managing multiple sclerosis
A. N. Bismillah*, S. D. P. Fielden*
Nat. Rev. Chem. 2024, 8, 793–794.

16
Kinetically Controlled and Nonequilibrium Assembly of Block Copolymers in Solution
S. D. P. Fielden*
J. Am. Chem. Soc. 2024, 146, 18781–18796

15
Harnessing Cytosine for Tunable Nanoparticle Self-Assembly Behavior Using Orthogonal Stimuli
S. J. Parkinson, S. D. P. Fielden, M. Thomas, A. J Miller, P. D. Topham, M. J. Derry, R. K. O’Reilly*
Biomacromolecules 2024, 25, 4905–4912.

14
Flexibility from fluxionality (invited News and Views article highlighting this paper)
S. D. P. Fielden*
Nat. Synth. 2024, 3, 296–298.

13
Crown ether active template synthesis of rotaxanes
S. D. P. Fielden*
ChemSystemsChem 2024, 6, e202300048.
Featured on the front cover.

12
Controlled node growth on the surface of polymersomes
M. Thomas, S. Varlas, T. R. Wilks, S. D. P. Fielden,* R. K. O'Reilly*
Chem. Sci. 2024, 15, 4396–4402.
featured in #MyFirstChemSci 2024 collection

11
Triggered polymersome fusion
S. D. P. Fielden,* M. J. Derry, A. J. Miller, P. D. Topham, R. K. O’Reilly*
J. Am. Chem. Soc. 2023, 145, 5824–5833.

10
Transamidation-driven molecular pumps
L. Binks, C. Tian, S. D. P. Fielden, I. J. Vitorica-Yrezabal, D. A. Leigh*
J. Am. Chem. Soc. 2022, 144, 15838–15844.
Highlighted in Chemistry World

9
Knotting matters: orderly molecular entanglements
Z. Ashbridge, S. D. P. Fielden, D. A. Leigh*, L. Pirvu, F. Schaufelberger, L. Zhang
Chem. Soc. Rev. 2022, 51, 7779-7809
Featured on the cover.

8
A Catalysis-Driven Artificial Molecular Pump
S. Amano, S. D. P. Fielden, D. A. Leigh*
Nature, 2021, 594, 529–534.

7
A molecular endless (74) knot
D. A. Leigh,* J. J. Danon, S. D. P. Fielden, J.-F. Lemonnier, G. F. S. Whitehead, S. L. Woltering.
Nat. Chem. 2021, 13, 117–122.
Featured on the front cover.
Highlighted in Nat. Chem. 2021, 13, 114–16, Matter 2021, 4, 2582-2584, Nature 2020, 588, 541, Chemistry World and elsewhere.

6
Single-Step Enantioselective Synthesis of Mechanically Planar Chiral [2]Rotaxanes Using a Chiral Leaving Group Strategy
C. Tian,+ S. D. P. Fielden,+ B. Pérez-Saavedra, I. J. Vitorica-Yrezabal, D. A. Leigh.*
J. Am. Chem. Soc. 2020, 142, 9803–9808.
Highlighted in Synfacts 2020, 16, 0917.

5
Weak functional group interactions revealed through metal-free active template rotaxane synthesis
C. Tian,+ S. D. P. Fielden,+ G. F. S. Whitehead, I. J. Vitorica-Yrezabal, D. A. Leigh.* (contribution order, +equal contribution)
Nat. Commun. 2020, 11, 744.
Featured in Nat. Commun. Focus: Nanoscale & Supramolecular Chemistry
Highlighted in Synfacts 2020, 16, 0405.

4
Dissipative Catalysis with a Molecular Machine
C. Biagini, S. D. P. Fielden, D. A. Leigh,* F. Schaufelberger, S. Di Stefano, D. Thomas.
Angew. Chem. Int. Ed. 2019, 58, 9876–9880.
Selected as a Hot Paper.
Featured on the cover.

3
Spontaneous assembly of rotaxanes from a primary amine, crown ether and electrophile
S. D. P. Fielden, D. A. Leigh,* C. T. McTernan, B. Pérez-Saavedra, I. J. Vitorica-Yrezabal.
J. Am. Chem. Soc. 2018, 140, 6049–6052.
Highlighted in Nat. Chem. 2023, 15, 1481–1483.

2
Molecular Knots
S. D. P. Fielden, D. A. Leigh,* S. L. Woltering
Angew. Chem. Int. Ed. 2017, 56, 11166–11194

1
Rotary and linear molecular motors driven by pulses of a chemical fuel
S. Erbas-Cakmak, S. D. P. Fielden, U. Karaca, D. A. Leigh,* C. T. McTernan, D. J. Tetlow, M. R. Wilson.
Science 2017, 358, 340–343.
